• A generally applicable strategy to screen for

  2020-07-27

  

  A generally applicable strategy to screen for improved α-KGD activity could be based on the generation of succinate by the decarboxylation of α-KG [49]. In this context, Escherichia coli strains were engineered, in which succinate-producing enzymes from the TCA an American idol were deleted. Growth

• br Introduction Primases have an important function in

  2020-07-27

  

  Introduction Primases have an important function in DNA replication. They synthesize de novo, on single-stranded DNA (ssDNA), a primer that is then extended by DNA polymerases. In the context of the replisome, primer synthesis is repeatedly required on the lagging strand. Although DNA primases ar

• It is well known that A peptide is

  2020-07-27

  

  It is well known that Aβ peptide is a neurotoxin and it is broadly used to mimic Alzherheimer’s disease (AD), condition to explore the mechanisms behind neuronal death in such diseases. In an in vitro study, Cheung et al. (2011) showed that the exposure of cultured neurons to Aβ results in cell deat

• Cytochromes P CYP are a superfamily of hemoproteins

  2020-07-27

  

  Cytochromes P450 (CYP 450) are a superfamily of hemoproteins containing a heme cofactor, which are widely distributed in animals, plants and microbes (Hannemann et al., 2007). CYP450 exhibits a variety of biological functions including biotransformation of drugs, detoxification of endogenous and xen

• Comparing the levels of the chemokine receptors CCR and CXCR

  2020-07-27

  

  Comparing the levels of the chemokine receptors CCR-5 and CXCR-4 an increase in the receptors levels were found in patients with PTSD and APD, and in patients diagnosed only with PTSD. In the group of women with APD and PTSD versus women with only APD a double increase in the level of CXCR-4 was rev

• Similarly research ranking RESEARCH was not significant in t

  2020-07-27

  

  Similarly, research ranking (RESEARCH) was not significant in the model so H7 is not supported. Contrary to the findings of Bline et al., 2016b, Boone et al., 2006, the current study did not find an association between faculty research productivity and exam pass rate. This could be due to difference

• The relationship between the hazard

  2020-07-27

  

  The relationship between the hazard function and the survivor function (see more details in Allison\'s textbook [1]) is described as or as Hence, we can estimate the survival probability from the hazard function. In survival analysis, the hazard function can be represented by any probability distrib

• br Acknowledgments The authors gratefully

  2020-07-27

  

  Acknowledgments The authors gratefully acknowledge the financial support from the Knut and Alice Wallenberg Foundation (KAW 20012.0067) and the Swedish Research Council (2016-04187). We would like to thank the people at the Center of tropical forest research, Smithsonian Tropical Research Institu

• br The remainder of this paper is structured as

  2020-07-27

  

  The remainder of this paper is structured as follows: Section 2 presents related work on existing literature reviews closely related to our study. Section 3 presents the research method. The results are presented in Section 4 and discussed in Section 5. Section 6 concludes the paper. Related wo

• Meanwhile high levels of extraversion have been associated

  2020-07-27

  

  Meanwhile, high levels of extraversion have been associated with weaker conditioning and faster GSK 2830371 learning (Eysenck, 1970). Similar to neuroticism/anxiety, the role of extraversion for fear conditioning and extinction has found only limited empirical support (Rauch et al., 2005) with sever

• br Introduction DNA ligation is required during DNA replicat

  2020-07-25

  

  Introduction DNA ligation is required during DNA replication and to complete almost all DNA repair events. In human cells, the DNA ligases encoded by three LIG genes are responsible for joining interruptions in the phosphodiester backbone [1]. These enzymes have distinct but overlapping functions

• Kim et al reported for bioactive compounds originating from

  2020-07-25

  

  Kim et al. reported for bioactive compounds originating from the endemic species in Korea, the hexane and EtOAc fractions of the MeOH extracts from the roots of Dystaenia takeshimana (Nakai) Kitagawa (Umbelliferae) showed cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX) dual inhibitory activity b

• Enzalutamide The CLC proteins in Arabidopsis

  2020-07-25

  

  The CLC proteins in Arabidopsis have been studied in some detail, and a total of seven genes (named AtCLCa-AtCLCg) have been identified (Lv et al., 2009). It is interesting that AtCLCa-AtCLCd and AtCLCg define a distinct phylogenetic branch that is closely related to eukaryotic CLCs, while the other

• br Introduction Our understanding of how ligands

  2020-07-25

  

  Introduction Our understanding of how ligands interact with G protein coupled receptors is evolving, particularly the recognition that some have the ability to preferentially activate a subset of intracellular signalling cascades – so called pathway biased ligands [1]. Additionally, it is now acc

• Metal ions are known not to be necessary

  2020-07-25

  

  Metal ions are known not to be necessary for catalytic activity of serine proteinases. Nevertheless, Co2+ and Ca2+ ions were found to stabilize glutamyl endopeptidase molecule [1], [7], [19]. In our previous study, we have described significant stimulating effect of Ca2+, Mg2+, and Co2+ on biosynthe

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