Previous studies reported that the introduction

2018-10-20

Previous studies reported that the introduction of KitW41 or KitWv mutations into BALB-RG or NSG mice could render mouse HSCs uncompetitive to donor human HSCs (Cosgun et al., 2014; McIntosh et al., 2015). They also showed that human HSPCs injected at a high dose (5 × 104 to 3 × 105 CD34+ CB cells),

Our system is very similar to that developed

2018-10-20

Our system is very similar to that developed by the Poss Lab using the same ubiquitin promoter fragment (Chen et al., 2013), although their study did not use sedation routinely for BLI acquisition and allowed animals to swim freely (donor BLI was assessed 28 days post-HCT). By optimizing sedation an

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2018-07-29