• Con el ltimo golpe de Estado argentino la persecuci n

  2019-04-28

  

  Con el último golpe de Estado argentino, la persecución de las sexualidades disidentes se intensificó aún más llegando LJI308 su paroxismo en toda la historia nacional. En este caso no se trataba de una persecución exclusiva de homosexuales, sino que se hallaba enmarcada en una descarnada persecució

• This report illustrates an unusual case of

  2019-04-28

  

  This report illustrates an unusual case of CMML which transformed to AML rapidly with emergence of the rare e6a2 fusion transcript. The possibility CML in blasts crisis was excluded as the CMML biopsy showed dysgranulopoiesis and lacked Ph chromosome and BCR-ABL1 fusion transcript. We further revi

• hdac inhibitors br Indigenous communities experience some of

  2019-04-28

  

  Indigenous communities experience some of the highest rates of suicide globally, especially among young people. This worrying epidemic has already been shown in Inuit communities of North America and Greenland and the Amazonian groups of Guyana, but recently has been shown to extend to Australian

• br With respect to the welfare of

  2019-04-28

  

  With respect to the welfare of children and mothers, the transition from the Millennium Development Goals (MDGs) to Sustainable Development Goals (SDGs) is sometimes perceived as risky. The relevant MDGs had a focus on interventions to address maternal and child health, while the focus of the SDGs

• Results from the present study also showed improvement in ti

  2019-04-26

  

  Results from the present study also showed improvement in timelines for measles immunisation, which is scheduled at 9 months of age, almost a gap of 6 months from the last vaccine according to EPI schedule for LMICs. Although the major focus up until now has been on reminder messages, the impact of

• It is generally believed that the

  2019-04-26

  

  It is generally believed that the pelvis is possibly the most accurate bone in the human body for gender determination, with the accuracy being 95% when completed. In addition, it is estimated that the accuracy of gender identification from the subpubic angle, ventral arc, and composite is approxima

• Education is part of the foundation for a

  2019-04-26

  

  Education is part of the foundation for a successful ASP. A well-designed educational program provides prescribers with updated knowledge on antimicrobial use, drug resistance, and infectious disease management. Educational interventions have been shown to improve prescribing competency, change pres

• In our study acute toxicities were mild and there

  2019-04-26

  

  In our study, acute toxicities were mild, and there were no Grade 3 or above hematologic toxicities. Only one patient (3.2%) had Grade 3 esophagus toxicity and three patients (9.7%) had Grade 3 lung toxicity. Compared with studies that investigated regimens of oxaliplatin and 5-FU/leucovorin, the pr

• Development of an atrial esophageal fistula

  2019-04-26

  

  Development of an atrial–esophageal fistula is one of the most dreaded complications of AF ablation [78]. A relatively large-scale nonrandomized study revealed that the anatomical risk factor of a small LA-to-esophageal distance was the most important factor in esophageal ulceration when using an ir

• Introduction Bone is a very

  2019-04-26

  

  Introduction Bone is a very dynamic tissue resulting from coordinated phases of formation and resorption called bone remodelling. Additional to its role in phosphocalcic homoeostasis, bone remodelling process is necessary for bone growth, for renewal of cellular and extracellular matrix components

• br Introduction Multiple signal transduction pathways in nor

  2019-04-26

  

  Introduction Multiple signal transduction pathways in normal and malignant nicotinic receptors converge on Bcl-2 family proteins, which stand at the crossroads between cell survival and apoptosis. The seminal event in the intrinsic pathway of apoptosis is mitochondrial outer membrane permeabiliz

• Introduction The hippocampus is a critical brain region for

  2019-04-26

  

  Introduction The hippocampus is a critical brain region for episodic memory formation in rodents and humans [1]. Hippocampal neurons, especially CA1 neurons, are highly vulnerable to ischemic injury [2], and failure of hippocampal function causes memory impairment and reduced cognitive ability [3,4

• br Possible reasons for the divergent results

  2019-04-26

  

  Possible reasons for the divergent results for the predictive value of PES for cardiac events First, there were methodological differences in the stimulation protocols used for PES, including the number of extrastimuli, the minimum coupling interval used (up to 200ms or refractoriness), the site

• The greater relative importance of indirect

  2019-04-25

  

  The greater relative importance of indirect causes could be a result of successful addressing of direct complications of pregnancy and childbirth, and of a change in risk factors and disease patterns. Indirect causes of death include the effects of pre-existing disorders, such as HIV infection, ment

• monooxygenase To overcome these resistance mechanisms in APL

  2019-04-25

  

  To overcome these resistance mechanisms in APL cells, a number of drugs have been tested. Tamibarotene is approximately 10 times more potent than ATRA as an in vitro inducer of differentiation, and is chemically more stable than ATRA [5]. Although the precise mechanism of the combination of tamibaro

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