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Further complicating matters is that although menopause can
2019-06-06

Further complicating matters is that although menopause can increase serum BTMs, other normal physiological conditions, certain disease states, and drugs are also associated with elevated BTM concentrations [81–83]. Low body-mass index (BMI) is a risk factor for low bone density [84] and evidence ha
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The patient was consented to treatment on clinical
2019-06-06

The patient was consented to treatment on clinical trial NCT02527447 and received treatment with salvage chemotherapy of mitoxantrone 12mg/m2/day IV on days 1–3, etoposide 200mg/m2/day continuous IV infusion (CIV) on days 8–10, and cytarabine 500mg/m2/day CIV on days 1–3 and 8–10 (EMA). Infectious p
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(S)-Crizotinib cost India is the second largest consumer and
2019-06-06

India is the second largest consumer and third largest producer of tobacco in the world. The Indian Government has been significantly engaged in addressing the tobacco problem. A major policy, the Cigarettes and Other Tobacco Products Act (COTPA) was implemented in 2003, followed by WHO\'s Framework
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At least genes are associated with familial
2019-06-06

At least 15 genes are associated with familial LQTS, with 3 of these genes accounting for 70–75% of cases [5]. Despite advances in the understanding of the molecular basis of LQTS, challenges remain in making the clinical diagnosis. Importantly, between 10–40% of gene carriers have normal QT interva
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Lead fracture was observed in of
2019-06-06

Lead fracture was observed in 4 of 1092 leads (0.37%); verified and incomplete lead fractures were observed in three (0.27%) and one lead (0.09%), respectively. All these fractures occurred in leads implanted by the SVP method; no fractures were observed in leads implanted by the CVC method (p Disc
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br SANTA CRUZ ACATLA Y SAN CRIST BAL QOLQANPATA
2019-06-06

SANTA CRUZ ACATLA Y SAN CRISTÓBAL QOLQANPATA EN LOS PRIMEROS TIEMPOS DE LA EVANGELIZACIÓN Consumada la conquista de México-Tenochtitlan en 1521 y la de Cusco en 1533-1534, los dos espacios vecinales, motivo del análisis que ofrecemos en este artículo, fueron considerados piezas angulares en el pr
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Two studies are ongoing that promise
2019-06-05

Two studies are ongoing that promise to be paramount in the prescription of dexamethasone in the prophylaxis of pain flare. NCIC CTG is currently investigating the use of 8mg dexamethasone daily on the day of treatment and four days post-treatment versus placebo of the same duration (NCT01248585) [1
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br Conflict of interest br Case presentation
2019-06-05

Conflict of interest Case presentation A 41-year-old man with a history of palpitations refractory to multiple antiarrhythmic agents for several weeks was referred to our department. A 12-lead electrocardiogram (ECG) demonstrated incessant narrow QRS complex tachycardia (cycle length of 580ms)
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br Conflict of interest br Introduction br
2019-06-05

Conflict of interest Introduction Cholangiocytes Cholangiocytes are epithelial transferase lining the intra and extrahepatic ducts of the three-dimensional network of the biliary tree. Biliary cells comprise approximately 3–5% of cells in the liver and are considered as one of the main cel
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Economic sanctions have exacerbated the
2019-06-05

Economic sanctions have exacerbated the brutality of this conflict many-fold, removing any prospects for peace and reconciliation. We need some reality to gauge their manifold effects before Syria descends into another Iraq, the devastating health consequences of which were well documented. Syria u
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A partir de una profunda
2019-06-05

A partir de una profunda revisión de sus concepciones teórico-políticas, los protagonistas de Controversia se ubicaron al interior de esta última perspectiva. Los marxistas dejaban de definir SRT 1720 la democracia como una “máscara de la dominación burguesa” y la izquierda peronista renunciaba a ig
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br Methods br Results br Discussion br Conclusions
2019-06-05

Methods Results Discussion Conclusions Conflict of interest statement Introduction Pulmonary vein (PV) isolation using a conventional electrode catheter is an effective therapy for atrial fibrillation (AF) [1,2]. However, it requires a long procedure time and has occasionally been
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mdm2 p53 br OPG RANK and RANKL contribute to the vicious
2019-06-05

OPG, RANK and RANKL contribute to the vicious cycle established between tumour mdm2 p53 and bone microenvironment: evidences for sarcomas and carcinomas RANK/RANKL axis is involved in the tumorigenic process RANK/RANKL axis is associated with the bone metastastic process, and as several argum
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The animal model described here is
2019-06-05

The animal model described here is also expected to lead us to design mechanism-based therapeutic interventions for bone metastases of NB. In this context, it is notable that the selective COX-2 inhibitor NS-398, which is known to selectively inhibit COX-2 without affecting COX-1 activity [30], inhi
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br Conclusion Elevated levels of the myocardial damage marke
2019-06-05

Conclusion Elevated levels of the myocardial damage markers c-TNT and H-FABP were not found after ≤10J-DT (9J or 10J) in patients who underwent device implantation. Our findings confirm that minimally-invasive DT has an acceptable success rate. To prevent unnecessary myocardium damage, ≤10J-DT ma
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