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Recent studies have reported that miR plays an important rol
2021-05-10

Recent studies have reported that miR-454 plays an important role in various cellular processes and diseases, such as inflammation, infection, osteogenic differentiation, and cancers [25,27,29,30]. Multiple evidence has documented that miR-454 promotes the proliferation, migration and invasion, and
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MTEP hydrochloride Biochemically the primary function of
2021-05-10

Biochemically, the primary function of PPIP5K2 is 1-kinase-mediated phosphorylation of 5-IP7 to form 1,5-IP8 (Shears, 2018). To a lesser extent, PPIP5K2 also phosphorylates IP6 to produce 1-IP7. Furthermore, PPIP5K2 has been shown to catalyze a reverse reaction, that is, dephosphorylation of 1,5-IP8
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Palifosfamide Many studies have documented that enolase acts
2021-05-10

Many studies have documented that enolase acts as a plasminogen-binding protein and this interaction is involved in the tissue invasion and pathogenicity of the causative agents (Almeida et al., 2004; Avilan et al., 2000; Marcilla et al., 2007; Mundodi et al., 2008; Vanegas et al., 2007). Furthermor
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Materials and methods br Results Assay of botulinum
2021-05-10

Materials and methods Results Assay of botulinum toxin activity is critical for the risk-assessment, diagnosis, and treatment of botulism cases. The frequently encountered active forms of the toxin are; L chain (inside intoxicated neuronal cells), BoNT (in the blood stream of a botulism patient,
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Carmoxirole hydrochloride br Acknowledgements br Introductio
2021-05-10

Acknowledgements Introduction Three structurally related fungal metabolites have been isolated from chloroform extracts of submerged rice cultures of Aspergillus terreus 23-1 from stored unhulled rice in Taiwan; these were named territrems A–C to indicate their biological origin (A. terreus) a
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br Results and discussion br
2021-05-10

Results and discussion Conclusion Recent studies showed that EGFR signaling is involved in inflammatory response in several inflammatory conditions. The normal inflammatory macrophage bromfenac show EGFR-dependent production of inflammatory mediators. Nevertheless, the development of EGFR inh
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To date many studies have reported significant aberrant
2021-05-10

To date, many studies have reported significant aberrant methylation patterns in TIMPs in various types of cancer CRA-024781 synthesis [[16], [17], [18]]. However, little has been reported on the events that lead to the methylation of TIMPs in the UV-irradiated human skin. Therefore, the objective
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br DGAT proteins lipid droplets and cancer
2021-05-10

DGAT proteins, lipid droplets and cancer cells Conclusions and future directions Conflicts of interest Acknowledgements This work was supported by NIH grants GM062887, P01CA097132, and Veterans Affairs Merit Award to LMO. Introduction Bioethanol and biodiesel are regarded as the two
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br General Characteristics of the Type II
2021-05-10

General Characteristics of the Type II Dehydrogenases Alternative NAD(P)H dehydrogenases conduct the reaction of the rotenone-insensitive oxidation of cytosolic and mitochondrial matrix NADH and/or NADPH (Fig. 1) (Melo et al., 2004, Rasmusson et al., 2004, Rasmusson et al., 2008). They catalyze t
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br Materials and methods br Results The frequency of
2021-05-10

Materials and methods Results The frequency of hypermethylation of RARbeta, RASSF1A, FHIT, GSTP1, MGMT, VHL and DAPK in patients with primary LSCC was assessed in both the tumor tissue samples and macroscopically and histologically normal mucosa from distant sites of the surgical specimen, PFT
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DDR distribution in healthy fibrotic and inflamed tissues Wh
2021-05-10

DDR1 distribution in healthy, fibrotic and inflamed tissues Whereas we can easily mine publicly available databases to infer DDR1 expression profile in different tissues (as reported in Fig. 1), fine comprehension of DDR1 biology has been hampered by the absence of a commercially available specific
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br Future direction and conclusion
2021-05-10

Future direction and conclusion Conflict of interest References and recommended reading Papers of particular interest, published within the period of review, have been highlighted as: Introduction Colony stimulating factor-1 (CSF-1; also referred to as the macrophage-colony stimulating
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In summary our findings indicate that bFGF
2021-05-08

In summary, our findings indicate that bFGF stimulates CPT1 expression, FA oxidation and lactate production with the participation of PPARβ/δ activation. On the other hand, this investigation shows that FSH concomitantly regulates the expression of genes involved in FA metabolism and in mitochondria
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br Introduction The endeavor to achieve
2021-05-08

Introduction The endeavor to achieve a successful use of commercial-off-the-shelf (COTS) electronic devices in space is not new and the reasons are well known [1], [2], [3]. More recently, COTS have been widely employed in the manufacturing of low-cost, small satellites, for scientific and even c
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By using the C elegans Matrisome Annotator tool we
2021-05-08

By using the C. elegans Matrisome Annotator tool, we found substantial enrichment for matrisome Tenofovir Disoproxil Fumarate receptor in these data sets. Thus, re-analyzing -omic datasets with the C. elegans Matrisome Annotator tool may be useful to generate novel hypotheses about the role of the
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