• At present many methods have been

  2022-04-18

  

  At present, many methods have been applied for multiple detection. For example, acetylcholine inhibitor [[9], [10], [11]] is frequently used to detect multiple targets because of its exquisite sensitivity and specificity, but it is difficult to design experiments to test short-length oligonucleotid

• We have isolated various bioactive peptides acting by bindin

  2022-04-18

  

  We have isolated various bioactive monobenzone acting by binding to the receptors of endogenous bioactive peptides such as opioid, bradykinin, neurotensin, and complements C3a and C5a etc. [24]. Rubimetide is the first example of an agonist peptide of the FPR2 of exogenous origin. Anxiolytic-like

• The presence of FBP in nuclei seems to accompany the

  2022-04-18

  

  The presence of FBP2 in nuclei seems to accompany the cells' potential to divide as it has been shown that during differentiation of the satellite cells (myogenic progenitor cells) the amount of nuclear FBP2 decreases and in differentiated myotubes, the localisation of FBP2 is restricted to cytoplas

• br Methods br Results br Discussion In the general populatio

  2022-04-16

  

  Methods Results Discussion In the general population BNP has been established as a marker for CNQX failure diagnosis. Moreover, there is growing evidence that elevated levels of natriuretic-peptides may improve CV risk prediction in the general population above traditional risk factors [[1

• Furthermore Rosethorne and Charlton Panula et al Reher

  2022-04-16

  

  Furthermore, Rosethorne and Charlton (Panula et al., 2015, Reher et al., 2012, Rosethorne and Charlton, 2011) expressed the human H4R in an osteosarcoma cell line and found that with respect to [35S]GTPγS binding, JNJ-7777120 acted as a neutral antagonist or very weak inverse agonist, a finding whic

• Recently the spectrin cytoskeleton a deformable actin associ

  2022-04-16

  

  Recently, the spectrin cytoskeleton, a deformable actin-associated network, has been identified as a modulator of Yki function, potentially acting both apically and basally in different cell types [75•, 76•, 77•]. Several mechanisms have been proposed, including regulation via Crb/Ex tethering [], t

• Apoptosis is one of critical toxic

  2022-04-16

  

  Apoptosis is one of critical toxic mechanisms of benzene metabolites. In this work, overexpression of HIF-1a could significantly reduce the increase in cell apoptosis caused by 40 μM BQ. At the meanwhile, anti-apoptotic protein Bcl-2 level was significantly elevated in HIF-1a overexpression cells th

• sphingosine Second although HO expression in the stromal

  2022-04-16

  

  Second, although HO-1 expression in the stromal macrophages has been seen in the other cancer tissues [21], the impact of HO-1 expression on EAOC progression has not been explored. We have found that the CD163+ M2-like sphingosine were HO-1+ in OE, but malignant transformation may be associated wit

• Our investigation also showed NAC increased the level

  2022-04-16

  

  Our investigation also showed NAC increased the level of DAF and might protect HUVECs from complement activation. NAC, an antioxidant/mucous modifier, has displayed benefits in chronic obstructive pulmonary disease. Martinez de Lizarrondo et al [38] provided evidence that the molecular target underl

• br Conclusion and future perspectives In the

  2022-04-16

  

  Conclusion and future perspectives In the setting of myocardial I/R stress, HDAC activity is induced and contributes to myocardial injury. HDAC inhibition appears to protect the jak stat pathway from I/R injury by activating a variety of pro-survival molecular pathways. From a clinical relevance

• Beckman Coulter s DxN VERIS Molecular Diagnostics System DxN

  2022-04-16

  

  Beckman Coulter’s DxN VERIS Molecular Diagnostics System (DxN VERIS System) is a fully automated system for the quantitative analysis of molecular targets, integrating sample introduction, nucleic DY131 extraction, reaction set-up, real-time PCR amplification and detection using TaqMan® chemistry,

• Our results show that deletion of the

  2022-04-16

  

  Our results show that deletion of the first loop of Obg does not abolish the augmentation of the GTPase activity of CgtAvc, revealing that the first loop is mainly responsible for the anchoring of the protein in the 50S and the transient interaction with ribosome is enough for augmentation of GTPase

• Of what interest is the link between

  2022-04-16

  

  Of what interest is the link between GSNOR and NO in the plant response to Fe deficiency? On the one hand, NO acts as an important signal to help plants accommodate Fe deficiencies; on the other hand, surplus NO is indeed a harmful RNS that induces severe S-nitrosylation-related damage at a higher s

• In summary we have successfully identified a

  2022-04-16

  

  In summary, we have successfully identified a series of potent and selective GSNOR inhibitors having imidazole and tetrazole functional groups in both end of the core structure and many compounds have been identified with IC: Introduction Peppers (Capsicum annuum L.), tomatoes and potatoes, belon

• The physiological and pharmacological roles of GPR remain la

  2022-04-16

  

  The physiological and pharmacological roles of GPR81 remain largely unclear because of several reasons. The low potency of lactate agonizing GPR81 in the millimolar range, together with its fast metabolic turnover, renders as a challenge in in vivo studies using lactate. Furthermore, there are no po

15958 records 441/1064 page Previous Next First page 上5页 441442443444445 下5页 Last page