Recent studies indicate that the canonical

2018-10-20

Recent studies indicate that the canonical Wnt pathway affects BMSC osteogenic differentiation. Wnt signaling can promote osteoblastic precursor differentiation into more differentiated osteoblasts and can serve as a negative regulator of adipogenesis (Glass et al., 2005; Krishnan et al., 2006). Thi

br Results br Discussion In the present

2018-10-20

Results Discussion In the present study we show that LPA1 is expressed by stem and progenitor colony stimulating factor 1 receptor (predominantly type 1 and type 2a) within the neurogenic niche of the dentate gyrus of adult mice, and that it outperforms Nestin, the current gold standard, as a

br Experimental Procedures br Author

2018-10-20

Experimental Procedures Author Contributions Acknowledgments The authors thank Chyuan-Sheng Lin from the Transgenic Mouse Facility at the Herbert Irving Comprehensive Cancer Center at Columbia University for development of the Zfyve27-CreERT2 mice; Theresa Swayne from the Confocal and Speci

Previous studies reported that the introduction

2018-10-20

Previous studies reported that the introduction of KitW41 or KitWv mutations into BALB-RG or NSG mice could render mouse HSCs uncompetitive to donor human HSCs (Cosgun et al., 2014; McIntosh et al., 2015). They also showed that human HSPCs injected at a high dose (5 × 104 to 3 × 105 CD34+ CB cells),

Our system is very similar to that developed

2018-10-20

Our system is very similar to that developed by the Poss Lab using the same ubiquitin promoter fragment (Chen et al., 2013), although their study did not use sedation routinely for BLI acquisition and allowed animals to swim freely (donor BLI was assessed 28 days post-HCT). By optimizing sedation an

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2018-07-29