• Two other groups subsequently published further data on

  2019-05-23

  

  Two other groups subsequently published further data on iPSCs models of ARVC that have improved our understanding of this disease. Kim et al. developed iPSC models using episomal methods from 2 ARVC patients, as well as with PKP2 mutations . Detailed electrophysiological characterization of mutant

• Obesity with excessive fat was

  2019-05-23

  

  Obesity with excessive fat was an important risk factor for the occurrence or progression of cardiac arrhythmia. As compared to abdominal fat, the amount of epicardial fat more correlates with the occurrences of atrial fibrillation, which suggests the distinctive arrhythmogenic effects of epicardial

• Examples of numerically generated vortices and their organiz

  2019-05-23

  

  Examples of numerically generated vortices and their organizing centers in 3-D excitable media are illustrated in Fig. 1. Panels a to d show 4 different configurations of 3-D scroll waves that were computed using the FitzHugh–Nagumo model [39,40]. Panel a shows an example of the simplest configurati

• There is a concern about the possibility that

  2019-05-23

  

  There is a concern about the possibility that some patients with WPW syndrome who have LV dyssynchrony and atypical delta waves, as in the present case, may be diagnosed with DCM. In these WPW syndrome patients, although medical therapy might not improve LV dysfunction, RFCA of the AP might improve

• kinesin inhibitor Abstract Background Substantial progress h

  2019-05-23

  

  Abstract Background Substantial progress has been made in reducing the incidence and prevalence of malaria. In 2016, 111 countries have eliminated malaria and another 35 countries, are making progress toward elimination of the disease. However, little is known about how much governments and donors

• The so called driver hypothesis has been posited in the

  2019-05-22

  

  The so-called driver arn-509 has been posited in the recent years. Optical mapping studies in isolated sheep hearts have suggested that at least some cases of AF can be maintained by high-frequency reentrant sources (rotors), usually located in the posterior LA, which result in spatially distribute

• br La profesionalizaci n del poeta como un perfil

  2019-05-22

  

  La profesionalización del poeta como un perfil creador La oferta sin precedentes que se ha experimentado en el terreno poético luego de varias iniciativas editoriales públicas y privadas en los años 1980-2010 (por ejemplo, Gabriel Bernal Granados o León Plascencia Ñol: 235) ha generado una bonanz

• oxytocin antagonist br Although killed whole cell oral

  2019-05-22

  

  Although killed, whole-cell oral cholera vaccines (OCVs) have been known to be efficacious since 1986, and the bivalent whole-cell vaccine Shanchol has been licensed in India since 2009, OCV was not regarded as useful for controlling cholera outbreaks until recently. Many public health officials q

• br es resultado de una larga investigaci n de

  2019-05-22

  

  es resultado de una larga investigación de la obra de Juan Rulfo, pero es asimismo el fruto de largas reflexiones sobre “el arte de narrar” en general y sobre las relaciones que la literatura entabla con la cultura y la historia en que se inscribe, conexiones ellas mismas históricas. Desde el artí

• br A hallmark of the past decade has

  2019-05-22

  

  A hallmark of the past decade has been the remarkable progress made in reducing maternal and child mortality, an achievement credited in some measure to the Millennium Development Goals. The reduction in child deaths from an estimated 12·7 million under-5 deaths in 1990 to fewer than 6 million dea

• br Conflict of interest br Introduction Acute kidney

  2019-05-22

  

  Conflict of interest Introduction Acute kidney injury in patients who are receiving anti-cancer treatments is an uncommon but serious complication. Such injury is often induced by nephrotoxic agents or urinary tract obstruction by space-occupying lesions. Among the many possible causes for ren

• br Discussion False tendons are

  2019-05-22

  

  Discussion False tendons are usually benign, intraventricular myocardial structures, which may cause a musical murmur [1], rate-dependent ventricular extrasystoles, functional mitral regurgitation, or deformation of the LV cavity due to mechanical stretch and dilatation of the LV wall [1,2]. Fals

• In addition to inducing IKs dysfunction through

  2019-05-22

  

  In addition to inducing IKs dysfunction through dominant-negative loss-of-function effects and defective channel trafficking, mutations in KCNQ1 suppress IKs channel function by reducing the channel affinity of interacting proteins [68,69]. Phosphatidylinositol-4,5-bisphosphate (PIP2) is a cofactor

• abiraterone acetate For single shot techniques like the CBA

  2019-05-22

  

  For single-shot techniques, like the CBA, a modified spiral mapping catheter has been introduced for the identification of PVPs prior to ablation and also for monitoring purposes during the ablation process [6]. The Achieve™ Mapping Catheter (AC) is an intra-cardiac electrophysiological diagnostic c

• Eligio Mar a Ancona Castillo naci en la ciudad de

  2019-05-22

  

  Eligio María Ancona Castillo nació en la ciudad de Mérida, el 1° de diciembre de 1836. Después de cursar los estudios elementales en la escuela de su padre, inició los cursos preparatorios en el Seminario Conciliar de San Ildefonso. Más tarde se inscribió en la Universidad del Estado para iniciar la

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